Endocrine Abstracts

Background: Isolated adrenocorticotropic hormone (ACTH) deficiency is a rare entity defined by secondary adrenal insufficiency and normal secretion of all other pituitary hormones. Delays in adrenal insufficiency (AI) diagnosis frequently encounter among older patients because of non-specific symptoms. The occurrences of actual or incipient adrenal crises following coronavirus disease 2019 (COVID-19) vaccine administration are increasingly reported over the last year after vac...

Background: Recent advances in next-generation sequencing technology have greatly increased the number of Variants of Uncertain Significance (VUS) encountered in clinical practice. Herein, we present difficulty in diagnostic path and challenges in a premenopausal woman with an unusual fracture history and osteoporosis.Clinical Case: A 37-year-old Thai woman with no known underlying disease was diagnosed with osteoporosis (a BMD Z-score of -2.6 a...